Work

Biotunable Acoustic Node Assembly of Organoids

Year: 2015

Type: article

Abstract: Bioengineering of 3D microtissues from cell spheroids is demonstrated by employing the vibration of acoustic standing waves and its hydrodynamic effect at the bottom of a liquid-carrier chamber. A large number of cell spheroids (>10(4) ) are assembled in seconds into a closely packed structure in a scaffold-free fashion under nodal pattern of the standing waves in a fluidic environment.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201500279

Authors: Pu Chen, Sinan Güven, Osman Berk Usta, Martin L. Yarmush, Utkan Demirci

Institutions: Stanford Medicine, Stanford University, Harvard University, Massachusetts General Hospital, Shriners Hospitals for Children - Boston, Rutgers, The State University of New Jersey

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering, National Center for Advancing Translational Sciences

Awards: G1479784716, G1932930224, Nano-Acoustic Masonry of Microgels for Bottom-Up Tissue Engineering, G4005945735, G5944361864, G7219215977, G78733395, Bio-MicroElectroMechanical Systems (BioMEMS) Resource Center

OpenAlex ID: W1939599893

FWCI: 3.623

Cites: 40

Cited by: 125

Related to: 10