Work

CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

Year: 2015

Type: article

Source: Cell

DOI: 10.1016/j.cell.2015.07.038

Authors: Ya Guo, Quan Xu, Daniele Canzio, Jia Shou, Jinhuan Li, David U. Gorkin, Inkyung Jung, Haiyang Wu, Yanan Zhai, Yuanxiao Tang, Yichao Lu, Yonghu Wu, Zhilian Jia, Wei Li, Michael Q. Zhang, Bing Ren, Adrian R. Krainer, Tom Maniatis, Qiang Wu

Institutions: Shanghai Jiao Tong University, Renji Hospital, Shanghai Cancer Institute, State Key Laboratory of Oncogene and Related Genes, Columbia University Irving Medical Center, University of California San Diego, Ludwig Cancer Research, The University of Texas at Dallas, Tsinghua University, Cold Spring Harbor Laboratory

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke

Awards: Computational Modeling of Mammalian Promoters, G28686511, G515113479, Protocadherin Gene Expression and Function, G666505512, Protocadherin Gene Expression and Function, Targeting Transcription and Splicing in Cancer, San Diego IRACDA Scholars Program, CSHL Cancer Center Support Grant

OpenAlex ID: W1941076503

FWCI: 43.23

Cites: 71

Cited by: 958

Related to: 10