Work

Hydrogels: Hydrogel Retaining Toxin‐Absorbing Nanosponges for Local Treatment of Methicillin‐Resistant Staphylococcus aureus Infection (Adv. Mater. 22/2015)

Year: 2015

Type: article

Abstract: On page 3437, L. Zhang and co-workers describe a hybrid nanomaterial, integrating unique toxin-absorbing nanosponges with hydrogels, that is developed for local anti-virulence therapy against methicillin-resistant Staphylococcus aureus (MRSA) infection. The hydrogel effectively retains the toxic nanosponges post administration without compromising toxin transport into the gel for neutralization. The nanosponge–hydrogel hybrid markedly reduces MRSA skin lesion development in a mouse model.

Source: Advanced Materials

DOI: 10.1002/adma.201570149

Authors: Fei Wang, Weiwei Gao, Soracha Thamphiwatana, Brian T. Luk, Pavimol Angsantikul, Qiangzhe Zhang, Che‐Ming J. Hu, Ronnie H. Fang, Jonathan A. Copp, Dissaya Pornpattananangkul, Weiyue Lu, Liangfang Zhang

Institutions: Fudan University, University of California San Diego, Moores Cancer Center, Key Laboratory of Smart Drug Delivery, Ministry of Education, Chulalongkorn University

Language: English

Topic: Hydrogels: synthesis, properties, applications

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W1941094111

FWCI:

Cites:

Cited by: 2

Related to: 10