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Identification of minireovirus as a Norwalk-like virus in pediatric patients with gastroenteritis

Year: 1994

Type: article

Abstract: In 1977, 30- to 32-nm virus-like particles, named minireovirus because of their unique morphologic appearance, were detected by electron microscopy in the stools of infants and young children with gastroenteritis. Sequence analysis of approximately 2,800 consecutive bases derived from overlapping PCR clones of a recent minireovirus clinical isolate showed 52% nucleotide sequence identity with the Norwalk virus sequence and, in addition, demonstrated that the genomic organizations of these two viruses were similar. Our data show that minireovirus is a Norwalk-like virus and should now also be included in the Caliciviridae family.

Source: Journal of Virology

DOI: 10.1128/jvi.68.5.3391-3396.1994

Authors: J F Lew, M Petric, A Z Kapikian, X Jiang, M K Estes, K Y Green

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases

Language: English

Topic: Viral gastroenteritis research and epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: U.S. Public Health Service