Work

Pharmacotherapy in post-traumatic stress disorder: evidence from randomized controlled trials.

Year: 2009

Type: review

Abstract: This review discusses evidence-based pharmacotherapies for post-traumatic stress disorder (PTSD). The epidemiology of PTSD and its phenomenological characteristics are summarized. Focus is placed on the major classes of drugs for which at least a minimum of evidence-based outcome data are available from randomized controlled trials (RCTs). Drugs for the total symptom constellation of the disorder, specific PTSD symptoms, such as nightmares, and prevention of PTSD development post-trauma, are discussed. Where appropriate, RCT methodological problems that limit the conclusions drawn are discussed. In addition, recommendations for research to fill critical gaps in the knowledge of PTSD treatment are offered.

Source: PubMed

Authors: Gregory M Sullivan, Yuval Neria

Institution: Columbia University

Language: English

Topic: Posttraumatic Stress Disorder Research

Subfield: Clinical Psychology

Field: Psychology

Domain: Social Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Institute of Mental Health

Award: Brain Circuitry and Psychological Predictors of PTSD