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M OLECULAR T HEORY OF H YDROPHOBIC E FFECTS : “She is too mean to have her name repeated.”

Year: 2002
Type: review
Abstract: This paper reviews the molecular theory of hydrophobic effects relevant to biomolecular structure and assembly in aqueous solution. Recent progress has resulted in simple, validated molecular statistical thermodynamic theories and clarification of confusing theories of decades ago. Current work is resolving effects of wider variations of thermodynamic state, e.g., pressure denaturation of soluble proteins, and more exotic questions such as effects of surface chemistry in treating stability of macromolecular structures in aqueous solution.
DOI: 10.1146/annurev.physchem.53.090401.093500
Language: English
Open Access status: green
Funders: U.S. Department of Energy, National Aeronautics and Space Administration, Rensselaer Polytechnic Institute, Johns Hopkins University, Vassar College, National Institutes of Health, Ames Research Center, Laboratory Directed Research and Development, Los Alamos National Laboratory
OpenAlex ID: W1948756557
FWCI: 1.37
Cites: 226
Cited by: 317
Related to: 10