Work

Sequence analysis of the gtfB gene from Streptococcus mutans

Year: 1987

Type: article

Abstract: The nucleotide sequence of the gtfB gene from Streptococcus mutans GS-5, coding for glucosyltransferase I activity, was determined. The gene codes for a strongly hydrophilic protein with a molecular size of 165,800 daltons. The deduced amino acid sequence revealed a typical gram-positive bacterial signal sequence at the NH2 terminus of the protein and 3.5 direct repeating units (each containing 65 amino acids) at the COOH terminus. Nucleotide sequencing of the region immediately downstream from the gtfB gene revealed the presence of a putative gene coding for an extracellular protein. This open reading frame is partially homologous to the gtfB gene.

Source: Journal of Bacteriology

DOI: 10.1128/jb.169.9.4263-4270.1987

Authors: T Shiroza, S Ueda, H K Kuramitsu

Institution: Northwestern University

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Dental and Craniofacial Research

Awards: G2388256804, G673371051