Work

Nramp1 and Other Transporters Involved in Metal Withholding during Infection

Year: 2015
Type: review
Abstract: During the course of infection, many natural defenses are set up along the boundaries of the host-pathogen interface. Key among these is the host response to withhold metals to restrict the growth of invading microbes. This simple act of nutritional warfare, starving the invader of an essential element, is an effective means of limiting infection. The physiology of metal withholding is often referred to as "nutritional immunity," and the mechanisms of metal transport that contribute to this host response are the focus of this review.
Institution: Harvard University
Language: English
Subfield: Hematology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W1952983243
FWCI: 1.974
Cites: 101
Cited by: 134
Related to: 10