Year: 2015
Type: article
Abstract: The accumulation of nociceptive diseases that limit normal body functions is a major risk factor for a disability, and visceral pain is one of the most prevalent human health problems. Additionally, many pain-associated diseases are accompanied by the concomitant decline in cognitive and motor performance. The complex interplay and balance between diverse signal transduction mediators, genetic background and environmental factors may ultimately determine the outcome of nociceptive progression in various disorders. Pain is a subjective feeling that is difficult to standardize and parameterize in a traditional fashion for scientific analysis. The causes of visceral pain are often not very clear, as there are many symptoms of the reproductive, gastrointestinal, musculoskeletal, neurological, psychological systems and urinary tract that often co-occur in the same patient. VIscero-somatic and viscero-viseral hyperalgesia andallodynia Cause the perception of pain to spread for an initial area, to adjacent visceral sites (Pan and Malykhina, 2014). Often times, there is not a clear relationship between the severity. There is often no clear relationship between the severity of the visceral pain and pathology in the viscera, including the reproductive tract, urinary bladder and colon. The clinician treating this pain is often times tempted to adopt a unidimensional approach, focusing on one organ system, ignoring the psychological and behavioral manifestations of the visceral pain. Therefore, studies of the nervous system in individuals with visceral pain associated with reproduction such as Chronic Pelvic Pain (CPP) syndrome, urinary system such as Painful Bladder Syndrome (PBS) and bowel disorders such as Irritable Bowel Syndrome (IBS), suggest a model in which alteration in the central stress circuits in predisposed individuals may trigger and then maintain, the pain and pathophysiological changes in the viscera (Mayer, 2011). These patients have significantly more depression, psychological and somatic complains and more often give a history of physical, sexual or emotional abuse, or trauma. Chronic visceral pain results in adverse affects not only one’s mood, but also their professional and social lives, as well as general well-being; the quality of life issues can affect the severity of pain, degree of impairment resulting from a painful condition and success of treatment modalities in alleviating pain.
Author: Victor V. Chaban
Language: English
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W1954443323