Year: 2011
Type: dissertation
Abstract: Acute pancreatitis is an important disease in companion animal medicine, and diagnostic methodology available to veterinary practitioners is often limited.Evidence based principles for the management of this common disease are also lacking.This thesis explores the current diagnostics of canine pancreatitis and management of this condition, reviewing the literature across both the veterinary and human medical fields.Assessment of the specificity of canine pancreatic-specific lipase (cPL) was made in a post-mortem study and calculated to be 82-92%, with a correlating sensitivity of 45-55%.A multi-centre study of dogs presenting with clinical signs consistent with acute pancreatitis to assess a new laboratory test, serum canine pancreatic elastase-1 (cPE-1) was also performed.This test had a sensitivity ranging from 66-79%, with a specificity of 92%.The sensitivity of both laboratory tests was greater in dogs with severe disease.To assess potential treatment options, a clinical severity score was established, with gut health, respiratory complications, cardiac complications, and blood pressure Studies within this thesis were supported by the European College of Veterinary
Author: Caroline Mansfield
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Murdoch University
OpenAlex ID: W1961320955