Work

Synthesis of C2‐Symmetric Dimeric ReI Peptide Complexes

Year: 2013

Type: article

Abstract: The reaction of [Re(CO)3(H2O)3]Br or [Re(CO)5Cl] with two peptides, glycylglycine, or glycylalanine were investigated. Each reaction produced a unique, well‐defined product. Structural elucidation showed the formation of chiral compounds with the formula [Re(CO)3(Gly‐Xxx‐O)]2, Xxx = Gly (1), Ala (2). Each dimer displays C2 symmetry and a nearly rectangular shape. The ligands are bound through the amine and amide carbonyl at a rhenium center and through the pendant carboxylate to the adjacent rhenium center. Both products are fully characterized by X‐ray structure elucidation.

Source: European Journal of Inorganic Chemistry

DOI: 10.1002/ejic.201201444

Authors: Richard S. Herrick, Christopher J. Ziegler, Kathryn L. Kennedy, Calvin Luu, James T. Engle

Institutions: College of the Holy Cross, University of Akron

Language: English

Topic: Inorganic and Organometallic Chemistry

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: The synthesis and screening of rhenium carbonyl compounds as technetium models, Synthesis and Screening of Peptide and Protein Based Rhenium Carbonyl Compounds a