Work

Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing.

Year: 2003

Type: article

Source: PubMed

Authors: Melissa L Fishel, Young R Seo, Martin L Smith, Mark R Kelley

Institutions: Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis

Language: English

Topic: DNA Repair Mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke

Awards: OXIDATIVE DNA DAMAGE AND REPAIR IN CNS CELLS, DOSE INTENSIFICATION BY GENE TRANSDUCTION IN CANCER, APE EXPRESSION/LEUKEMIA RESPONSE TO CHEMO/RADIOTHERAPY

OpenAlex ID: W1962237327

FWCI: 1.93

Cites: 57

Cited by: 74

Related to: 10