Work

Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications

Year: 2015

Type: review

Abstract: Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interactions in real-time with high sensitivity and without the need of labels. This review article discusses a wide range of applications in optical-based sensors using either surface plasmon resonance (SPR) or surface plasmon resonance imaging (SPRI). Here we summarize the principles, provide examples, and illustrate the utility of SPR and SPRI through example applications from the biomedical, proteomics, genomics and bioengineering fields. In addition, SPR signal amplification strategies and surface functionalization are covered in the review.

Source: Sensors

DOI: 10.3390/s150510481

Authors: Hoang Nguyen, Jeho Park, Sebyung Kang, Moonil Kim

Institutions: Korea Research Institute of Bioscience and Biotechnology, Korea University of Science and Technology, Ulsan National Institute of Science and Technology, Tuskegee University

Language: English

Topic: Plasmonic and Surface Plasmon Research

Subfield: Atomic and Molecular Physics, and Optics

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,137

Funders: Korea Research Council of Fundamental Science and Technology, Korea Research Institute of Bioscience and Biotechnology