Year: 2012
Type: article
Abstract: This is a theoretical paper which examines at a game theoretical perspective the dynamics of cooperators and cheater cells under metabolic stress conditions and high spatial heterogeneity. Although the ultimate aim of this work is to understand the dynamics of cancer tumor evolution under stress, we use a simple bacterial model to gain fundamental insights into the progression of resistance to drugs under high competition and stress conditions.
Source: AIP Advances
DOI: 10.1063/1.3699043
Authors: Chris Cleveland, David Liao, Robert Austin
Institutions: Princeton University, University of California, San Francisco
Language: English
Subfield: Modeling and Simulation
Field: Mathematics
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,350
OpenAlex ID: W1963853088