Work

Subulatin, an Antioxidic Caffeic Acid Derivative Isolated from theIn VitroCultured Liverworts,Jungermannia subulata,Lophocolea heterophylla, andScapania parvitexta

Year: 2002

Type: article

Abstract: The new caffeic acid derivative, subulatin (1), was isolated from in vitro cultured liverworts, Jungermannia subulata, Lophocolea heterophylla, and Scapania parvitexta. The structure of 1 involved two caffeic acids, D-glucose, and 2-carboxy-6-(1,2-dihydroxy-ethyl)-4,5-dihydroxy-5,6-dihydro-4H-pyran. The connectivity of those and the absolute stereochemistry of 1 were elucidated on the basis of spectroscopic evidence. The antioxidative activity of 1 was comparable to that of alpha-tocopherol. (2'R)-Phaselic acid (2a) and (-)-9,2''-epiphylloyl-L-malic acid (4) were also isolated from J. subulata and L. heterophylla, respectively. A chiral HPLC analysis of the p-bromobenzoyl-malic acids derived from 2a showed that 2a from J. subulata was unusual (+)-trans-caffeoyl-D-malic acid.

Source: Bioscience Biotechnology and Biochemistry

DOI: 10.1271/bbb.66.255

Authors: Hiroyuki TAZAKI, Mayumi ITO, Masako MIYOSHI, Jun KAWABATA, Eri FUKUSHI, Takashi FUJITA, Mutsumi MOTOURI, Tatsuo FURUKI, Kensuke NABETA

Institutions: Obihiro University of Agriculture and Veterinary Medicine, Hokkaido University, Megmilk Snow Brand (Japan), Natural History Museum and Institute

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W1963860794

FWCI: 0.817

Cites: 23

Cited by: 25

Related to: 10