Year: 2014
Type: article
Abstract: The ability to accurately measure real-time pH fluctuations in-vivo could be highly advantageous. Early detection and potential prevention of bacteria colonization of surgical implants can be accomplished by monitoring associated acidosis. However, conventional glass membrane or ion-selective field-effect transistor (ISFET) pH sensing technologies both require a reference electrode which may suffer from leakage of electrolytes and potential contamination. Herein, we describe a solid-state sensor based on oxidized single-walled carbon nanotubes (ox-SWNTs) functionalized with the conductive polymer poly(1-aminoanthracene) (PAA). This device had a Nernstian response over a wide pH range (2-12) and retained sensitivity over 120 days. The sensor was also attached to a passively-powered radio-frequency identification (RFID) tag which transmits pH data through simulated skin. This battery-less, reference electrode free, wirelessly transmitting sensor platform shows potential for biomedical applications as an implantable sensor, adjacent to surgical implants detecting for infection.
Source: Scientific Reports
DOI: 10.1038/srep04468
Authors: Pingping Gou, Nadine D. Kraut, Ian M. Feigel, Hao Bai, Gregory J. Morgan, Yanan Chen, Yifan Tang, Kara Bocan, Joshua Stachel, Lee Berger, Marlin Mickle, Ervin Sejdić, Alexander Star
Institution: University of Pittsburgh
Language: English
Subfield: Bioengineering
Field: Chemical Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,690
Awards: G1386838626, G8976590660
OpenAlex ID: W1963928818