Work

The effect of iron depletion on chronic hepatitis C virus infection

Year: 2008

Type: article

Abstract: Increasing evidence exists that iron overload, a common finding in chronic hepatitis C virus (HCV) infection, plays an important role in the pathophysiology of this disease. The mechanisms by which iron excess induces liver damage along with the benefit of iron depletion via phlebotomy on biochemical and histological outcomes in patients with chronic HCV infection have been discussed in this review. Finally, we focus on the effect of iron reduction on the rate of response to interferon antiviral therapy.

Source: Hepatology International

DOI: 10.1007/s12072-008-9076-z

Authors: Massimo Franchini, Giovanni Targher, Franco Capra, Martina Montagnana, Giuseppe Lippi

Institutions: Azienda Ospedaliera Universitaria Integrata Verona, University of Verona

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,090