Fluorescence Polarization and Anisotropy in High Throughput Screening: Perspectives and Primer
Year: 2000
Type: article
Abstract: Fluorescence polarization and anisotropy are two nearly equivalent techniques that have together, over the past 5 years, achieved wide use in high throughput screening in drug discovery. These are single-label methods that can be used to construct homogeneous assays that are fast, sensitive, and resistant to some significant interferences. Moreover, the assays are relatively inexpensive. This review surveys the peer-reviewed literature on the subject and explores some of the fundamental issues that bear on assay performance.
Source: SLAS DISCOVERY
Author: John C. Owicki
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $2,070
OpenAlex ID: W1964381872