Work

Silencing of Lipid Metabolism Genes through IRE1α-Mediated mRNA Decay Lowers Plasma Lipids in Mice

Year: 2012

Type: article

Source: Cell Metabolism

DOI: 10.1016/j.cmet.2012.09.004

Authors: Jae-Seon So, Kyu Yeon Hur, Margarite Tarrio, Vera Ruda, Maria Frank-Kamenetsky, Kevin Fitzgerald, Victor Koteliansky, Andrew H. Lichtman, Takao Iwawaki, Laurie H. Glimcher, Ann-Hwee Lee

Institutions: Harvard University, Brigham and Women's Hospital, Massachusetts General Hospital, Alnylam Pharmaceuticals (United States), Gunma University, Japan Science and Technology Agency, RIKEN, Ragon Institute of MGH, MIT and Harvard, Massachusetts Institute of Technology

Language: English

Topic: Endoplasmic Reticulum Stress and Disease

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Heart, Lung, and Blood Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: From Sugar to Fat: How Transcription Factor XBP1 Regulates Hepatic Lipogenesis, Transcriptional Regulation of the Immune Response, Regulation of T Cell Responses in Atherosclerosis, Regulation of Triglyceride Metabolism by the transcription factor CREB-H

OpenAlex ID: W1964443702

FWCI: 6.881

Cites: 60

Cited by: 291

Related to: 10