Work

The design, synthesis, and evaluation of 8 hybrid DFG-out allosteric kinase inhibitors: A structural analysis of the binding interactions of Gleevec®, Nexavar®, and BIRB-796

Year: 2010

Type: article

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2010.05.063

Authors: Justin Dietrich, Christopher Hulme, Laurence H. Hurley

Institutions: University of Arizona, BIO5 Institute, University of Arizona Cancer Center

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Foundation for Cancer Research, Deutsche Forschungsgemeinschaft

OpenAlex ID: W1964596754

FWCI: 2.082

Cites: 38

Cited by: 195

Related to: 10