Work

A Kpnl polymorphism for the human insulin-responsive glucose transporter gene (GLUT4) on chromosome 17

Year: 1989

Type: article

Abstract: SOURCE/DESCRIPTION phJHT-3 encodes part of the major insulin responsive glucose transporter expressed in skeletal muscle, heart and adipose tissue.The 1.7 kb EcoRl-linked cDNA insert (vector-pBR327) includes 145bp of 5'-untranslated region, 1326 bp encoding amino acids 1-442 and 267 bp of an intron following codon 442 (T.Kayans et al., submitted).POLYMORPHISM KpnI detects a 2 allele polymorphism with bands at 6.5 kb and 5.8 kb.

Source: Nucleic Acids Research

DOI: 10.1093/nar/17.9.3621

Authors: N. Leysens, J.C. Murray, G.I. Bell

Institutions: University of Iowa Hospitals and Clinics, Howard Hughes Medical Institute, University of Chicago

Language: English

Topic: Metabolism, Diabetes, and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of General Medical Sciences, National Institute of Dental and Craniofacial Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development