Work

A fast and sensitive multiple sequence alignment algorithm

Year: 1989

Type: article

Abstract: A two-step multiple alignment strategy is presented that allows rapid alignment of a set of homologous sequences and comparison of pre-aligned groups of sequences. Examples are given demonstrating the improvement in the quality of alignments when comparing entire groups instead of single sequences. The modular design of computer programs based on this algorithm allows for storage of aligned sequences and successive alignment of any number of sequences.

Source: Computer applications in the biosciences

DOI: 10.1093/bioinformatics/5.2.115

Authors: Martin Vingron, Patrick Argos

Institutions: European Molecular Biology Laboratory, European Molecular Biology Laboratory, European Molecular Biology Laboratory

Language: English

Topic: Genomics and Phylogenetic Studies

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W1964795578

FWCI: 2.148

Cites: 21

Cited by: 108

Related to: 10