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How bacterial pathogens colonize their hosts and invade deeper tissues

Year: 2015
Type: review
Abstract: Bacterial pathogens have evolved a wide range of strategies to colonize and invade human organs, despite the presence of multiple host defense mechanisms. In this review, we will describe how pathogenic bacteria can adhere and multiply at the surface of host cells, how some bacteria can enter and proliferate inside these cells, and finally how pathogens may cross epithelial or endothelial host barriers and get access to internal tissues, leading to severe diseases in humans.
DOI: 10.1016/j.micinf.2015.01.004
Language: English
Subfield: Microbiology
Open Access status: hybrid
Estimated APC paid: $3,510
Funders: Howard Hughes Medical Institute, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Louis-Jeantet Foundation, Institut Pasteur, Institut National de la Recherche Agronomique
Awards: G1503714226, G1979782309, G282427092, G3256177976, G5759980, G6644745025, G7240651115, G7376787254, Integrative Biology of Emerging Infectious Diseases, Subversive pro- and anti-inflammation trade-offs promote infection by Listeria monocytogenes, G8670608220
OpenAlex ID: W1964954110
FWCI: 7.79
Cites: 100
Cited by: 796
Related to: 9