Short-Term Stability of Sleep and Heart Rate Variability in Good Sleepers and Patients with Insomnia: For Some Measures, One Night is Enough
Year: 2012
Type: article
Study design: Observational Study
Abstract: STUDY OBJECTIVES: Quantify the short-term stability of multiple indices of sleep and nocturnal physiology in good sleeper controls and primary insomnia patients. DESIGN: Intra-class correlation coefficients (ICC) were used to quantify the short-term stability of study outcomes. SETTING: Sleep laboratory. PARTICIPANTS: Fifty-four adults with primary insomnia (PI) and 22 good sleeper controls (GSC). MEASUREMENTS: Visually scored sleep outcomes included indices of sleep duration, continuity, and architecture. Quantitative EEG outcomes included power in the delta, theta, alpha, sigma, and beta bands during NREM sleep. Power spectral analysis was used to estimate high-frequency heart rate variability (HRV) and the ratio of low- to high-frequency HRV power during NREM and REM sleep. RESULTS: With the exception of percent stage 3+4 sleep; visually scored sleep outcomes did not exhibit short-term stability across study nights. Most QEEG outcomes demonstrated short-term stability in both groups. Although power in the beta band was stable in the PI group (ICC = 0.75), it tended to be less stable in GSCs (ICC = 0.55). Both measures of cardiac autonomic tone exhibited short-term stability in GSCs and PIs during NREM and REM sleep. CONCLUSIONS: Most QEEG bandwidths and HRV during sleep show high short-term stability in good sleepers and patients with insomnia alike. One night of data is, thus, sufficient to derive reliable estimates of these outcomes in studies focused on group differences or correlates of QEEG and/or HRV. In contrast, one night of data is unlikely to generate reliable estimates of PSG-assessed sleep duration, continuity or architecture, with the exception of slow wave sleep.
Source: SLEEP
DOI: 10.5665/sleep.2088
Institution: University of Pittsburgh
Language: English
Topic: Sleep and related disorders
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: bronze
Awards: G158648086, G2148195735, G2340992976, G2519210884, General Clinical Research Center, University of Pittsburgh Clinical and Translational Science Institute, G3981513740, G4023110948, G441474341, Sleep: A Novel Pathway Linking Major Depression and Cardiovascular Disease, G6913611223, G9000209890, G9000300514, Translational Research Training in Sleep and Circadian Science, EEG SLEEP STUDIES IN RELATION TO AFFECTIVE ILLNESS
OpenAlex ID: W1964973114