Work

A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity

Year: 2013

Type: article

Source: Nature Chemical Biology

DOI: 10.1038/nchembio.1404

Authors: Nicholas M Levinson, Steven G Boxer

Institution: Stanford University

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Awards: G1591908980, Kinome-Wide Spectroscopic Study of Drug Binding Site Electrostatics, ELECTROSTATICS AND DYNAMICS IN MYOGLOBIN MUTANTS, Electrostatics and Dynamics in Proteins

OpenAlex ID: W1965009739

FWCI: 5.179

Cites: 59

Cited by: 177

Related to: 10