Work

Synthesis of N4-(substituted phenyl)-N4-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells

Year: 2012

Type: article

Source: Bioorganic & Medicinal Chemistry

DOI: 10.1016/j.bmc.2012.12.010

Authors: Aleem Gangjee, Nilesh Zaware, Ravi Kumar Vyas Devambatla, Sudhir Raghavan, Cara D. Westbrook, Nicholas F. Dybdal-Hargreaves, Ernest Hamel, Susan L. Mooberry

Institutions: Duquesne University, The University of Texas at San Antonio Health Science Center, The University of Texas at San Antonio, National Institutes of Health, Frederick National Laboratory for Cancer Research, National Cancer Institute

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Texas at San Antonio, Duquesne University, National Institutes of Health, National Cancer Institute

Awards: G1143455775, Mays Cancer Center at UT Health SA, G1349582399, G3847248659

OpenAlex ID: W1965016283

FWCI: 0.442

Cites: 31

Cited by: 17

Related to: 10