Work

Monitoring digoxin therapy: I. Plasma concentrations and an in vitro assay of tissue response.

Year: 1977

Type: article

Abstract: 1 An in vitro technique is described for measuring the uptake of 86Rb by human erythrocytes. 2 Fifteen patients were treated with digoxin for atrial fibrillation and other fast arrhythmias. 3 86Rb uptake by the patients' own red cells fell from pre-treatment values during digitalization. 4 The therapeutic response of patients with atrial fibrillation correlated better with the changes in 86Rb uptake than with plasma digoxin concentrations.

Source: British Journal of Clinical Pharmacology

DOI: 10.1111/j.1365-2125.1977.tb00697.x

Authors: JK Aronson, DG Grahame‐Smith, KF Hallis, A Hibble, F Wigley

Institutions: John Radcliffe Hospital, University of Oxford, Medical Research Council

Language: English

Topic: Atrial Fibrillation Management and Outcomes

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1965496361

FWCI: 5.522

Cites: 27

Cited by: 46

Related to: 10