Work

Triangular Helical Column for Centrifugal Countercurrent Chromatography

Year: 2009

Type: article

Abstract: Effective column space and stationary phase retention have been improved by changing the configuration of the helical column originally used for toroidal coil countercurrent chromatography. The use of an equilateral triangular core for the helix column doubles effective column space and retains the stationary phase over 40% of the total column capacity without increasing the column pressure. The present results suggest that the stationary phase retention and the peak resolution will be further improved using new column designs fabricated by a new technology called "laser sintering for rapid prototyping."

Source: Journal of Liquid Chromatography & Related Technologies

DOI: 10.1080/10826070802671580

Authors: Yoichiro Ito, Henry Yu

Institutions: National Institutes of Health, National Heart, Lung, and Blood Institute

Language: English

Topic: Chromatography in Natural Products

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute

Award: Spiral Disk Assembly For High-speed Countercurrent Chromatography