Year: 1978
Type: article
Abstract: The ability of a cell or organism to direct its movement along a chemical gradient has fascinated biologists for over 100 yr. This process of chemotaxis requires transformation of directional information from the environment into a series of cellular responses resulting in directional movement. Many lower organisms including bacteria, protozoa, and slime molds exhibit chemotaxis. This ability helps them find nutrients, avoid noxious stimuli and aggregate at critical times in their development. Reports on higher organisms indicate that primordial germ cells (32, 36), neurons (123), tumor cells (124), and fibroblasts (115) exhibit chemotaxis. However, the leukocytes are the only vertebrate cells in which this ability has
Source: The Journal of Cell Biology
DOI: 10.1083/jcb.77.2.269
Author: SH Zigmond
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Science Foundation
OpenAlex ID: W1965809927