Work

Effect of Photodynamic Antimicrobial Chemotherapy on in vitro and in situ Biofilms

Year: 2012

Type: article

Abstract: AIM: The effect of photodynamic antimicrobial chemotherapy (PACT) on oral biofilms was evaluated. METHODS: Biofilms formed in vitro were treated with sensitizer (S) and/or light (L) in the test (S+L+) and control (S-L-, S+L-, S-L+) groups. Additionally, 21 volunteers wore intraoral devices and the biofilms formed on each side of the device were referred to as S+L+ or S-L- groups. RESULTS: Significant decreases in the viability of in vitro biofilms were observed after PACT. PACT was ineffective in inhibiting multi-species biofilms formed in situ. CONCLUSION: PACT was effective on in vitro biofilms and was ineffective on in situ biofilms.

Source: Caries Research

DOI: 10.1159/000341190

Authors: A.H. Teixeira, E.S. Pereira, L.K.A. Rodrigues, D. Saxena, S. Duarte, I.C.J. Zanin

Institutions: Universidade Federal do Ceará, New York University

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Conselho Nacional de Desenvolvimento Científico e Tecnológico