Obesity: A Transgenerational Problem Linked to Nutrition during Pregnancy
Year: 2012
Type: article
Abstract: The increased obstetric risks of maternal obesity have been well described. These include increased risks of gestational diabetes mellitus, preeclampsia, stillbirth, and cesarean delivery. The fetal/neonatal consequences of prenatal maternal obesity have received less attention. In addition to an increased risk of stillbirth, the fetal/neonatal consequences include increased adiposity and a metabolic status that increases the lifetime risk of obesity and diabetes. This review focuses on the clinical obstetric consequences of maternal obesity and highlights recent mechanistic insights on fetal programming as well as evidence suggesting that prenatal care provides a unique opportunity to ameliorate these risks and decrease the cycle of childhood obesity.
Authors: Kevin Grove, Antonio Frias
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
Awards: Maternofetal Signaling and Lifelong Consequences, SUPPORT FOR NATIONAL PRIMATE RESEARCH CENTER, Women's Reproductive Health Research Career Development, Interrupting the Vicious Cycle of Obesity and Metabolic Syndrome, Maternal High Fat Diet and Melanocortin System in Offspring, Support for National Primate Research Center, Vanderbilt Diabetes Research Center
OpenAlex ID: W1966038722