Work

Effect of C9-Methyl Substitution and C8-C9 Conformational Restriction on Antifolate and Antitumor Activity of Classical 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines

Year: 2000

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/jm000130i

Authors: Aleem Gangjee, Yibin Zeng, John J. McGuire, Roy L. Kisliuk

Institutions: Tufts University, Roswell Park Comprehensive Cancer Center, Duquesne University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Cancer Institute, National Institute of Allergy and Infectious Diseases

Awards: FOLYLPOLYGLUTAMATE SYNTHETASE IN CANCER CHEMOTHERAPY, G4495356350, STRUCTURE BASED ANALOGS AS ANTIOPPORTUNISTIC AGENTS

OpenAlex ID: W1966430390

FWCI: 1.114

Cites: 21

Cited by: 37

Related to: 10