Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice
Work
Year: 2013
Type: article
Abstract: ABT-263 and its structural analogues ABT-199 and ABT-737 inhibit B-cell lymphoma 2 (Bcl-2), BCL2L1 long isoform (Bcl-xL) and BCL2L2 (Bcl-w) proteins and promote cancer cell death. Here, we show that a... more
Source: Cell Death and Disease
Authors Laura Kakkola, Oxana V. Denisova, Janne Tynell, Johanna ViiliƤinen, Tine Ysenbaert +18 more
Institutions Institute for Molecular Medicine Finland, University of Helsinki, Finnish Institute for Health and Welfare, Ghent University, University of Turku +2 more
Cites: 38
Cited by: 56
Related to: 10
FWCI: 1.305
Citation percentile (by year/subfield): 83.29
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Sustainable Development Goal Good health and well-being
Open Access status: gold
APC paid (est): $3,422