Work

The FLT3 and PDGFR inhibitor crenolanib is a substrate of the multidrug resistance protein ABCB1 but does not inhibit transport function at pharmacologically relevant concentrations

Year: 2015

Type: article

Source: Investigational New Drugs

DOI: 10.1007/s10637-015-0205-y

Authors: Trevor J. Mathias, Karthika Natarajan, Suneet Shukla, Kshama A. Doshi, Zeba N. Singh, Suresh V. Ambudkar, Maria R. Baer

Institutions: University of Maryland, Baltimore, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, National Institutes of Health, National Cancer Institute, Center for Cancer Research

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Cancer Institute

Awards: G821304228, G9000273969, UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT

OpenAlex ID: W1966483376

FWCI: 0.78

Cites: 67

Cited by: 28

Related to: 10