Year: 2011
Type: article
Abstract: In a recent review, a putative fibrinogen-like protein in the protochordate Ciona intestinalis was noted. Unfortunately, computer-directed splicing had omitted several exons, mistakenly generating a single long polypeptide chain. In fact, 3 consecutive genes exist, the translated versions of which are homologous to individual vertebrate fibrinogen chains. The circulating form is likely a 6-chain covalent dimer, just as occurs in vertebrates.
Source: Journal of Innate Immunity
DOI: 10.1159/000329823
Author: Russell F. Doolittle
Institution: University of California San Diego
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1966729444