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Rational Design, Synthesis, Evaluation, and Crystal Structure of a Potent Inhibitor of Human GAR Tfase: 10-(Trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic Acid,

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Year: 2003
Type: article
Source: Biochemistry
DOI: 10.1021/bi034219c
Authors: Yan Zhang, Joel Desharnais, Thomas H. Marsilje, Chenglong Li, Michael P. Hedrick, Lata T. Gooljarsingh, Ali Tavassoli, Stephen J. Benkovic, Arthur J. Olson, Dale L. Boger, Ian A. Wilson
Institutions: Scripps Research Institute, Pennsylvania State University
Language: English

Topic: Biochemical and Molecular Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Cancer Institute, National Center for Research Resources
Awards: G1000054730, G3196197326, G342910812, GAR TFASE AND ATIC: STRUCTURE, MECHANISM AND INHIBITION, NATIONAL BIOMEDICAL COMPUTATION RESOURCE, A Computational Docking Resource for Cancer Research
OpenAlex ID: W1967300347
FWCI: 1.287
Cites: 1
Cited by: 46
Related to: 10
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