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Discovery of Bioactive Small-Molecule Inhibitor of Poly ADP-Ribose Polymerase: Implications for Energy-Deficient Cells

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Year: 2006
Type: article
Source: Chemistry & Biology
DOI: 10.1016/j.chembiol.2006.05.012
Authors: Stephen M. Altmann, Andrey Muryshev, Elisa Fossale, Michele M. Maxwell, Francine N. Norflus, Jonathan Fox, Steven M. Hersch, Anne B. Young, Marcy E. MacDonald, Ruben Abagyan, Aleksey G. Kazantsev
Institutions: Harvard University, Massachusetts General Hospital, Kurchatov Institute, Molsoft (United States), Scripps Research Institute
Language: English

Topic: PARP inhibition in cancer therapy
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke
Awards: G2811397197, G3241945294, G4239688072, Flexible Macromolecular Docking, Delineating the Huntington's disease mechanism by manipulating the mouse HD, G9000302121
OpenAlex ID: W1967366712
FWCI: 1.04
Cites: 24
Cited by: 10
Related to: 10
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