Work

B0 inhomogeneity‐insensitive triple‐quantum‐filtered sodium imaging using a 12‐step phase‐cycling scheme

Year: 2010

Type: article

Abstract: Triple-quantum-filtered (TQF) sodium MRI can be used to separate sodium NMR signals from different physiological compartments. Although three-pulse triple-quantum filtering has been demonstrated to be better suited for in vivo imaging, the absence of the refocusing pulse in the filter increases its sensitivity to magnetic field inhomogeneities. Therefore, several TQF cycles have been developed previously to correct image distortions caused by B(0) inhomogeneities. In this paper, we present a new 12-step phase-cycling TQF scheme based on three radiofrequency pulses which allows the compensation of B(0) variations both with and without ancillary B(0) map information. The method offers 40% higher signal-to-noise-ratio efficiency compared with the previously developed B(0)-correcting phase-cycling schemes.

Source: NMR in Biomedicine

DOI: 10.1002/nbm.1548

Authors: Lazar Fleysher, Niels Oesingmann, Matilde Inglese

Institutions: New York University, Siemens Healthcare (United States), NYU Langone Health

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute of Neurological Disorders and Stroke

Award: G892637757