Work

Does choice of sedative agent affect duration of ICU stay, mortality or neurological outcome in patients undergoing therapeutic hypothermia?

Year: 2009

Type: conference-abstract

Abstract: The effect of therapeutic hypothermia on sedative drug clearance and neurological prognostication is unknown. Hypothermia has been shown to affect clearance of drugs metabolised by the cytochrome p450 system (fentanyl, midazolam and muscle relaxants) [ 1 ]. We undertook a retrospective study to ascertain whether the use of remifentanil sedation was associated with reduced duration of ICU stay, ventilation, mortality or neurological outcome compared with fentanyl in patients undergoing therapeutic hypothermia.

Source: Critical Care

DOI: 10.1186/cc7564

Authors: M Gillies, R Pratt, J Borg, J Brooks, C Mckenzie, S Tibby

Institution: Guy's and St Thomas' NHS Foundation Trust

Language: English

Topic: Anesthesia and Sedative Agents

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,190