Year: 1981
Type: article
Abstract: A minimally invasive and standardized means of resuscitating cats from defined periods of ventricular fibrillation (VF) has been developed using methods little different from human cardiopulmonary resuscitation techniques. After a 12 min arrest, the rate of successful resuscitation is greater than 90%, witha resuscitation time of 2.5 +/- 0.7 (SD) min, and a 7 day survival of 70%. All deaths could be related to a specific electroencephalographic event observed acutely post-resuscitation, and were not due to obvious non-neurologic complications. The post-arrest variation in a variety of parameters (blood pressure, blood gases, etc.) was minimal, and the degree of neurologic damage was severe enough to permit evaluation. Such a model is clinically relevant, and may be useful in studying the pathophysiology of global ischemia, and assessing different types of post-arrest therapy.
Source: Stroke
Institution: University of California San Diego
Language: English
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W1967943152