Work

Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression

Year: 1997

Type: review

Abstract: Several studies in the past year have shown that the cell cycle events typically attributed to a response to growth factors actually require signals provided by both growth factors and the extracellular matrix. Moreover, at least some of these matrix-based effects seem to involve matrix-dependent organization of the cytoskeleton rather than cell adhesion per se. Overall, these studies are providing new insights into the long-appreciated concepts of anchorage- and shape-dependent growth.

Source: Current Opinion in Cell Biology

DOI: 10.1016/s0955-0674(97)80157-3

Authors: Richard K Assoian, Xiaoyun Zhu

Institution: University of Miami

Language: English

Topic: Cellular Mechanics and Interactions

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $4,390

Funder: National Institutes of Health