Work

Tunable, Temperature‐Responsive Polynorbornenes with Side Chains Based on an Elastin Peptide Sequence

Year: 2009

Type: article

Abstract: Live on: Random copolymers made by living ring-opening metathesis polymerization of norbornene monomers containing either the elastin peptide sequence -(VPGVG)- or pentaethylene glycol (see scheme; Mes=mesityl, pyr=pyridine) exhibit a lower critical solution temperature (LCST). The LCST can be easily modified by varying the ratio of the co-monomers in the polymer feed.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200903888

Authors: Rosemary M. Conrad, Robert H. Grubbs

Institution: California Institute of Technology

Language: English

Topic: Advanced Polymer Synthesis and Characterization

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funders: National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences

Awards: G172049764, Sympathetic Axonal Activity in Conscious Rats During Development of Hypertension, G3383006923, Organic Synthesis Reagents on Transition Metals, Design and Synthesis of Elastic Polymers for Use in Vascular Grafts