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Common Clinical Substitutions Enhance the Carbapenemase Activity of OXA-51-Like Class D β-Lactamases from Acinetobacter spp

Year: 2014

Type: article

Abstract: Carbapenem resistance in Acinetobacter baumannii is a growing threat to the effective treatment of nosocomial infections. Acquired carbapenemases (e.g., OXA-23, OXA-24, and their variants) are a major source of carbapenem resistance ([1][1]). A. baumannii has a chromosomal carbapenem-hydrolyzing

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.03651-14

Authors: Joshua M. Mitchell, David A. Leonard

Institution: Grand Valley State University

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1968571268

FWCI: 1.218

Cites: 14

Cited by: 25

Related to: 10