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Comorbid Migraine is Associated with a Negative Impact on Quality of Life in Patients with Major Depression

Year: 2005

Type: article

Abstract: This study investigated the impact of migraine on health-related quality of life (HRQoL) among patients with major depressive disorder (MDD). We prospectively enrolled 151 consecutive psychiatric out-patients meeting DSM-IV criteria for MDD. Migraine and other headache types were diagnosed based on the International Classification of Headache Disorders, 2nd edition (2004). The Short Form-36 (SF-36) was administered as a generic instrument of HRQoL. Among 151 patients with MDD, migraine (N = 73, 48.3%) was very common. Comorbidity of migraine predicted a significantly negative impact on all physical subscales and vitality but not on the other mental subscales of the SF-36 after controlling for depression, age and gender. The presence of migraine should be considered as an important physical symptom in clinic-based MDD samples. Simultaneous management of depression and severe headaches, especially migraine, might improve HRQoL in patients with MDD.

Source: Cephalalgia

DOI: 10.1111/j.1468-2982.2005.00985.x

Authors: C-I Hung, C-Y Liu, J-L Fuh, Y-Y Juang, S-J Wang

Institutions: Chang Gung University, Chang Gung Memorial Hospital, Taipei Veterans General Hospital, National Yang Ming University

Language: English

Topic: Migraine and Headache Studies

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Science Council, Chang Gung Medical Foundation