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A Rational Utilization of High-Throughput Screening Affords Selective, Orally Bioavailable 1-Benzyl-3-carboxyazetidine Sphingosine-1-phosphate-1 Receptor Agonists

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Year: 2004
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/jm0492507
Authors: Jeffrey J. Hale, Christopher L. Lynch, William Neway, Sander G. Mills, Richard Hajdu, Carol Ann Keohane, Mark J. Rosenbach, James A. Milligan, Gan-Ju Shei, Stephen A. Parent, Gary Chrebet, James Bergstrom, Deborah Card, Marc Ferrer, Peter Hodder, Berta Strulovici, Hugh Rosen, Suzanne Mandala
Institution: Merck & Co., Inc., Rahway, NJ, USA (United States)
Language: English

Topic: Sphingolipid Metabolism and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W1969141508
FWCI: 1.895
Cites: 10
Cited by: 87
Related to: 10
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