Work

Integration column: Biofunctional polymeric nanoparticles for spatio-temporal control of drug delivery and biomedical applications

Year: 2009

Type: review

Abstract: Polymeric nanoparticle technology has evolved from drug carrier design to advanced multifunctional macromolecular structures. They enable drug delivery and release of a bioactive under spatio-temporal control rather than just passive release by a long-circulating carrier. As such, the carrier is enabling the biomolecule or the bioactive to carry out its designed biological function. Due to their small size nanoparticles may also induce perturbations of biological systems different from any other biomaterials, therefore opening up new biomedical applications as well as raising concerns about adverse effects.

Source: Integrative Biology

DOI: 10.1039/b907627c

Authors: Dominique A. Rothenfluh, Jeffrey A. Hubbell

Institutions: University of Zurich, Universitätsklinik Balgrist, École Polytechnique Fédérale de Lausanne

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W1969155229

FWCI: 0.111

Cites: 62

Cited by: 15

Related to: 10