Work

Mitotic Control of Cancer Stem Cells

Year: 2013

Type: article

Abstract: Summary: Cancer stem cells are self-renewing, tumorigenic cells at the apex of tumor hierarchies, and postulated to be quiescent in many tumor types. This issue of Cancer Discovery highlights a study that links the presentation of kinetochores within mitosis to an essential requirement for BUB1B/BubR1, broadening our understanding of the cell-cycle machinery in cancer stem cells. Cancer Discov; 3(2); 141–4. ©2013 AACR. See related article by Ding et al., p. 198

Source: Cancer Discovery

DOI: 10.1158/2159-8290.cd-12-0588

Authors: Monica Venere, Tyler E. Miller, Jeremy N. Rich

Institutions: Cleveland Clinic, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green