Work

Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging

Year: 2006

Type: article

Abstract: We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed.

Source: Optics Express

DOI: 10.1364/oe.14.006739

Authors: Jang-Woo You, Teresa C. Chen, Mircea Mujat, B. Hyle Park, Johannes F. de Boer

Institutions: Korea Advanced Institute of Science and Technology, Massachusetts Eye and Ear Infirmary, Harvard University, Massachusetts General Hospital

Language: English

Topic: Optical Coherence Tomography Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,270