Work

New drugs from marine microbes: the tide is turning

Year: 2006

Type: article

Abstract: This is a mini-review demonstrating that investigation of the genomics of marine microbes from all three domains has the potential to revolutionize the search for secondary metabolites originally thought to be the product of marine invertebrates. The basis for the review was a symposium at the 2005 Annual Meeting of the SIM covering some aspects of the potential for marine microbes to be the primary producers of such metabolites. The work reported at that symposium has been integrated into a fuller discussion of current published literature on the subject with examples drawn from bacteria, cyanophytes and fungi.

Source: Journal of Industrial Microbiology & Biotechnology

DOI: 10.1007/s10295-006-0115-2

Authors: David J. Newman, Russell T. Hill

Institutions: Frederick National Laboratory for Cancer Research, National Cancer Institute, University of Maryland, Baltimore, University of Maryland Biotechnology Institute

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Applied Microbiology and Biotechnology

Field: Immunology and Microbiology

Domain: Life Sciences

Open Access status: bronze

Funder: National Science Foundation

Award: Microbial Observatories: Microbial Diversity of Procaryotes in Marine Sponges of the Class Demospongiae