Work

Putting RNAs in the right place at the right time: RNA localization in the frog oocyte

Year: 2005

Type: review

Abstract: Localization of maternal mRNAs in many developing organisms provides the basis for both initial polarity during oogenesis and patterning during embryogenesis. Prominent examples of this phenomenon are found in Xenopus laevis, where localized maternal mRNAs generate developmental polarity along the animal/vegetal axis. Targeting of mRNA molecules to specific subcellular regions is a fundamental mechanism for spatial regulation of gene expression, and considerable progress has been made in defining the underlying molecular pathways.

Source: Biology of the Cell

DOI: 10.1042/bc20040067

Authors: Mary Lou King, Timothy J. Messitt, Kimberly L. Mowry

Institutions: University of Miami, Brown University

Language: English

Topic: RNA Research and Splicing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze